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Metabolically healthy aging

  • Healthy aging = maintaining metabolic resilience
  • Not age, but visceral fat predicts vitality
  • Disrupted metabolism accelerates aging
  • TCR, exercise, sleep and stress are the pillars
  • Supplements can support, lifestyle remains foundation

Healthy aging means not so much avoiding diseases, but maintaining metabolic resilience — the body’s ability to smoothly switch between fat and glucose burning.

A disrupted metabolism accelerates aging; restoring metabolic balance slows it.


Aging is partly the result of:

  • Cellular damage from oxidative stress
  • Low-grade inflammation
  • Lack of recovery moments
EffectConsequence
Loss of fat burning capacityEnergy from fat is blocked
Less efficient mitochondriaLower energy production
Slowed recoveryCells regenerate less well

A metabolically healthy lifestyle restores precisely these processes — without medication or expensive supplements.


ProcessEffect
Lowering insulinReduces inflammatory activity
Sufficient fat burningPrevents fat storage in liver and muscles
Mitochondrial recoveryIncreases energy and endurance
AutophagyClears damaged cells, promotes regeneration

Therapeutic carbohydrate restriction (TCR) lowers insulin load and activates fat burning.

It’s not a temporary diet, but a sustainable way of eating that restores energy metabolism.

AdviceEffect
Avoid processed foodFast carbohydrates and seed oils
Use natural fatsOlive oil, butter, ghee, fatty fish
Sufficient protein1.2-1.6 g/kg body weight per day
Fermented productsHealthy microbiome
Periodic fasting16:8 or 24h per week stimulates autophagy

Goal: stable blood sugar, less oxidative stress, more energy.


Target areaTCR lifestyleSupplements
Energy & mitochondriaFats as fuel, fasting, exerciseNMN, PQQ, CoQ10
Inflammation & oxidationFewer seed oils, omega-3 from fishCurcumin, astaxanthin
Cell repair & autophagyFasting, sleep, stress recoveryQuercetin
Metabolism & insulinCarbohydrate restriction, muscle trainingBerberine
Muscle strength & recoveryProtein-rich diet, strength trainingCreatine, magnesium

DomainCore actionEffect
Sleep7-8 hours per night, fixed timesRecovery, hormone balance
NutritionUnprocessed, fat- and protein-rich, fermentedLower insulin, less inflammation
ExerciseStrength training, walking, outdoorsBetter fat burning
StressRest moments, breathing, cold/heatCortisol balance
SocialEngagement, purposeMental resilience

Veelgestelde vragen

What determines healthy aging?

Not age, but the amount of visceral fat and metabolic resilience. Visceral fat promotes inflammation, oxidation and insulin resistance. Restoring metabolic balance slows aging.

What is metabolic resilience?

The body's ability to smoothly switch between fat and glucose burning. With persistently high insulin, the body loses this ability, mitochondria become less efficient and recovery slows.

How does TCR support healthy aging?

Therapeutic carbohydrate restriction lowers insulin, activates fat burning, restores mitochondria and stimulates autophagy. It's not a temporary diet but a sustainable way of eating.

Which supplements support aging?

Supplements can be useful but lifestyle remains the foundation. Options: NMN, PQQ, CoQ10 (energy), curcumin, astaxanthin (inflammation), quercetin (cell repair), berberine (metabolism), creatine and magnesium (muscles).


Medische Disclaimer: De informatie van Stichting Je Leefstijl Als Medicijn over leefstijl, ziektes en stoornissen mag niet worden opgevat als medisch advies. In geen geval adviseren wij mensen om hun bestaande behandeling te veranderen. We raden mensen met chronische aandoeningen aan om zich over hun behandeling goed door bevoegde medische professionals te laten adviseren.

Medical Disclaimer: The information provided by Stichting Je Leefstijl Als Medicijn regarding lifestyle, diseases, and disorders should not be construed as medical advice. Under no circumstances do we advise people to alter their existing treatment. We recommend that people with chronic conditions seek advice regarding their treatment from qualified medical professionals.