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Fruit

  • Fruit contains a lot of fructose, which burdens the liver
  • The metabolic impact varies by person and type of fruit
  • Metabolically healthy people: 1-2 portions per day
  • With metabolic conditions: 0-1 portion, preferably berries
  • Avoid fruit juice, smoothies, and dried fruit

Fruit consists of water, fiber, vitamins, minerals, and especially sugars such as fructose, glucose, and sucrose.

Although fruit is often seen as healthy, the metabolic impact varies greatly by:

  • Person
  • Amount
  • Type of fruit

The amount of fructose largely determines the burden on the liver and the risk of metabolic dysregulation.


Most of the energy in fruit comes from fructose. Fructose is processed almost entirely in the liver.

With larger amounts, the following occurs:

  • Fat buildup in the liver (NAFLD/MASLD)
  • Rise in triglycerides
  • Increase in uric acid
  • Development of insulin resistance

EffectConsequence
Stimulating effect on liver fatVLDL production rises
Hepatic insulin resistanceLiver responds less to insulin
Low satietyOverconsumption occurs easily
High glucose contentRapid blood sugar spikes

Fruit provides:

  • Vitamin C
  • Potassium
  • Polyphenols
  • Fiber

SituationRecommendation
Metabolically healthy1-2 portions of whole fruit per day
Metabolic conditions0-1 portion per day
  • Insulin resistance
  • Prediabetes
  • Type 2 diabetes
  • Fatty liver (NAFLD/MASLD)
  • Hypertriglyceridemia
  • Elevated uric acid (gout)
  • Overweight
  • Fruit juice
  • Smoothies
  • Dried fruit (dates, raisins, etc.)

FruitNote
BerriesBlueberries, raspberries, blackberries — best choice
KiwiRelatively low in fructose
Citrus fruitsOrange, tangerine, grapefruit
Green appleLower in sugar than red apple
FruitNote
GrapesVery high in sugar
MangoHigh fructose load
BananaLots of sugar, especially ripe banana
PineappleHigh in sugar
Dried fruitDates, raisins — concentrated sugar

AdviceWhy
Eat fruit after a meal, not between mealsSlows absorption, limits glucose spike
With metabolic conditions, choose only berriesLowest fructose load
Combine fruit with protein or fatLimits glucose spikes
See fruit as supplement, not as staple foodVegetables are more important

Fruit can be part of a healthy lifestyle, but due to the high fructose load, overconsumption contributes to:

  • Fatty liver
  • Insulin resistance
  • Metabolic dysregulation

Veelgestelde vragen

Is fruit healthy?

Fruit contains vitamins, minerals, and fiber, but also a lot of fructose. The metabolic impact varies greatly by person, amount, and type of fruit. With metabolic conditions, selective and moderate use is essential.

How much fruit can I eat per day?

Metabolically healthy people can usually tolerate 1-2 portions of whole fruit per day. With insulin resistance, diabetes, fatty liver, or overweight, 0-1 portion per day is recommended, preferably berries.

Which fruit is best for metabolic conditions?

Berries (blueberries, raspberries, blackberries), kiwi, citrus fruits, and green apple have a lower fructose load. Avoid grapes, mango, banana, pineapple, and dried fruit due to high sugar load.

Why is fruit juice unhealthy?

Fruit juice and smoothies contain concentrated sugars without fiber, causing them to be absorbed quickly. This gives the same metabolic load as soft drinks: fatty liver, high triglycerides, and insulin resistance.


Medische Disclaimer: De informatie van Stichting Je Leefstijl Als Medicijn over leefstijl, ziektes en stoornissen mag niet worden opgevat als medisch advies. In geen geval adviseren wij mensen om hun bestaande behandeling te veranderen. We raden mensen met chronische aandoeningen aan om zich over hun behandeling goed door bevoegde medische professionals te laten adviseren.

Medical Disclaimer: The information provided by Stichting Je Leefstijl Als Medicijn regarding lifestyle, diseases, and disorders should not be construed as medical advice. Under no circumstances do we advise people to alter their existing treatment. We recommend that people with chronic conditions seek advice regarding their treatment from qualified medical professionals.